PUBLICATIONS | fuminori-tsuruta

Perinatal Reduction of Genetically Aberrant Neurons from Human Cerebral Cortex

Shao DD, Zhao Y, Ghosh U, Brew J, Zhao S, Qian X, Tran J, Taketomi T, Tsuruta F, Park PJ, Walsh CA.

bioRxiv, 2024 Oct 9:2024.10.08.617159. doi: 10.1101/2024.10.08.617159.

RBM3 enhances cold resistance by regulating thermogenic gene expressions

Nakamura J, Uno M, Taketomi T, Yadav MK, Tsuruta F* (*corresponding)

bioRxiv, doi: https://doi.org/10.1101/2023.05.10.540283

<2024>

Propagation of neuronal micronuclei regulates microglial characteristics

Yano S, Asami N, Kishi Y, Takeda I, Kubotani H, Hattori Y, Kitazawa A, Hayashi K, Kubo K, Saeki M, Maeda C, Hiraki C,

Teruya RI, Taketomi T, Akiyama K, Okajima-Takahashi T, Sato B, Wake H, Gotoh Y, Nakajima K, Ichinohe T, Nagata T, Chiba T, Tsuruta F* (*corresponding)

Nat Neurosci, in press

(Review)

Molecular basis of neuronal and microglial states in the aging brain and impact on cerebral blood vessels

Maeda C and Tsuruta F* (*corresponding)

Int J Mol Sci. 25: 4443 (2024)

USP4 regulates TUT1 ubiquitination status in concert with SART3

Kim J#, Taketomi T#, Yamada A, Uematsu Y, Ueda K, Chiba T, Tsuruta F* (#cofirst)(*corresponding)

Biochem.Biophys.Res.Commun. 701: 149557 (2024)

<2023>

(Review)

Towards an understanding of microglia and non-parenchymal macrophages

Taketomi T, Tsuruta F* (*corresponding)

Biology (Basel) 12: 1091 (2023)

Proteasome-Associated Proteins, PA200 and ECPAS, Are Essential for Murine Spermatogenesis

Sato B, Kim J, Morohoshi K, Kang W, Miyado K,Tsuruta F, Kawano N, Chiba T

Biomolecules 13: 586 (2023)

(Review)

ミクログリアの発生・分化・多様性獲得のメカニズム

浅見奈都・照屋林一郎・鶴田文憲

BIO Clinica 2023年3月号「proteinopathy最前線」 (Japanese)

(Review)

Mutations in Hevin/Sparcl1 and risk of autism spectrum disorder

Taketomi T, Tsuruta F* (*corresponding)

Neural Regen. Res. 18:1499-1500 (2023)

<2022>

Cold shock protein RBM3 is upregulated in the autophagy-deficient brain
Nakamura J, Aihara T, Chiba T, Tsuruta F* (*corresponding)

MicroPubl Biol. 2022 Dec 8:2022:10.17912/micropub.biology.000695.

(Review)

発達期ミクログリアの多様性制御

照屋林一郎・鶴田文憲

Medical Science Digest 2022年12月号「グリアデコード：新領域の発展性」 (Japanese)

Autism-associated mutation in Hevin/Sparcl1 induces endoplasmic reticulum stress through structural instability
Taketomi T, Yasuda T, Morita R, Kim J, Shigeta Y, Eroglu C, Harada R, Tsuruta F* (*corresponding)

Sci Rep 12: 11891 (2022)

Press release

Interview "筑波大学ポッドキャスト研究室サイドストーリー” (Japanese)

筑波大学新聞 "Hello, 先端研究” (Japanese)

<2021>

A MATLAB-based program for three-dimensional quantitative analysis of micronuclei reveals that neuroinflammation induces micronuclei formation in the brain

Yano S, Akiyama K, Tsuchiya R, Kubotani H, Chiba T, Nagata T*, Tsuruta F* (*co-corresponding)

Sci Rep 11: 18360 (2021)

Press release

Prevention of necrosis caused by transient expression in Nicotiana benthamiana by application of ascorbic acid

Nosaki S, Kaneko KM, Tsuruta F, Yoshida H, Kato Y, Miura K

Plant physiology 186:832-5 (2021)

(Review)

Exploring genes that control microglial heterogeneity and transition

Okajima T, Tsuruta F* (*corresponding)

Neural Regen. Res. 16:2397-2398 (2021)

<2020>

Atypical cadherin FAT3 is a novel mediator for morphological changes of microglia

Okajima T, Gu Y, Teruya R, Yano S, Taketomi T, Sato B, Chiba T, Tsuruta F* (*corresponding)

eNeuro. ENEURO.0056-20.2020 (2020)

USP15 deubiquitinates TUT1 associated with RNA metabolism and maintains cerebellar homeostasis

Kim J, Nakamura J#, Hamada C#, Taketomi T#, Yano S, Okajima T, Kashiwabara SI, Baba T, Sato B, Chiba T*, Tsuruta F*

(#equal contribution, *co-corresponding)

Mol. Cell Biol. 40:e00098-20 (2020)

Selected as a cover

<2018>

(Review)

Microglial dynamics during brain development

Okajima T, Tsuruta F* (*corresponding)

Neural Regen. Res. 13: 222-223 (2018)

<2017>

KLHL7 promotes TUT1 ubiquitination associated with nucleolar integrity: Implications for retinitis pigmentosa.

Kim J#, Tsuruta F#*, Okajima T, Yano S, Sato B, Chiba T*. (#co-first, *co-corresponding)

Biochem.Biophys.Res.Commun. 494: 220-226 (2017)

Quantification of endosome and lysosome motilities in cultured neurons using fluorescent probes.

Tsuruta F#*, Okajima T#, Yano S#, Chiba T. (#co-first, *corresponding)

J.Vis.Exp. 123: (2017)

CACUL1/CAC1 attenuates p53 activity through PML post-translational modification.

Fukuda T, Kigoshi-Tansho Y, Naganuma T, Kazaana A, Okajima T, Tsuruta F*, Chiba T*.(*co-corresponding)

Biochem.Biophys.Res.Commun. 482:863-869 (2017)

<2016>

USP15 stabilizes the transcription factor Nrf1 in the nucleus, promoting the proteasome gene expression.

Fukagai K, Waku T, Chowdhury AM, Kubo K, Matsumoto M, Kato H, Natsume T, Tsuruta F, Chiba T, Taniguchi H, Kobayashi A.

Biochem.Biophys.Res.Commun. 478:363-70 (2016)

SCFFbl12 Increases p21Waf1/Cip1 Expression Level through Atypical Ubiquitin Chain Synthesis.

Tsuruta F*, Takebe A, Haratake K, Kanemori Y, Kim J, Endo T, Kigoshi Y, Fukuda T, Miyahara H, Ebina M, Baba T, Chiba T*

(*co-corresponding)

Mol.Cell Biol. 36:2182-94 (2016)

KIAA0368-deficiency affects disassembly of 26S proteasome under oxidative stress condition.

Haratake K, Sato A, Tsuruta F, Chiba T

J.Biochem. 159:609-18 (2016)

(Review)

Cold shock as a possible remedy for neurodegenerative disease

Aihara T, Tsuruta F* (*corresponding)

Int J Neurol Neurother. 3:053 (2016)

Microglia: The new players in regulating the brain development.

Tsuruta F

Curr. Neurobiol. 7:54-55 (2016)

New insights into the functions of PtdIns(3,5)P2 in the pathogenesis of neurodegenerative disorders.

Tsuruta F

Neural Regen. Res. 11:240-241 (2016)

<2015>

PIKfyve mediates the motility of late endosomes and lysosomes in neuronal dendrites.
Tsuruta F* and Ricardo Dolmetsch RE (*corresponding)
Neurosci.Lett. 605:18-23 (2015)

The intronic region of Fbxl12 functions as an alternative promoter regulated by UV irradiation.

Tsuruta F*, Kim J, Fukuda T, Kigoshi Y, Chiba T*　(*co-corresponding)
Biochem.Biophys.Rep. 3:100-107 (2015)

CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2.

Kigoshi Y, Fukuda T, Endo T, Hayasaka N, Iemura S, Natsume T, Tsuruta F, Chiba T
Sci. Rep. 5:12857 (2015)

<2013>

Myeloma overexpressed 2 (Myeov2) regulates L11 subnuclear localization through Nedd8 modification.

Ebina M#, Tsuruta F#*, Katoh MC, Kigoshi Y, Someya A, Chiba T* (#co-first, *co-corresponding)

PLoS ONE 8:e65285 (2013)

Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis.

Qian MX, Pang Y, Liu CH, Haratake K, Du BY, Ji DY, Wang GF, Zhu QQ, Song W, Yu Y, Zhang XX, Huang HT, Miao S, Chen LB,

Zhang ZH, Liang YN, Liu S, Cha H, Yang D, Zhai Y, Komatsu T, Tsuruta F, Li H, Cao C, Li Wei, Li GH, Cheng Y, Chiba T, Wang L,

Goldberg AL, Shen Y, Qui XB

Cell 153:1012-1024 (2013)

Competition between a-actinin and Ca2+-calmodulin controls surface retention of the L-type Ca2+ channel CaV1.2.

Hall DD, Dai S, Tseng PY, Malik Z, Nguyen M, Matt L, Schnizler K, Shephard A, Mohapatra DP, Tsuruta F, Dolmetsch RE, Christel CJ,

Lee A, Burette A, Weinberg RJ and Hell JW

Neuron 78:483-497 (2013)

Brap2 regulates temporal control of NF-kB localization mediated by inflammatory response.

Takashima O#, Tsuruta F#, Kigoshi Y, Nakamura S, Kim J, Katoh MC, Fukuda T, Irie K, Chiba T. (#co-first)

PLoS ONE 8:e58911 (2013)

Cytoplasmic location of a1A voltage-gated calcium channel C-terminal fragment (Cav2.1-CTF) aggregate as sufficient to cause cell death.

Takahashi M, Obayashi M, Ishiguro T, Sato N, Niimi Y, Ozaki K, Mogushi K, Mahmut Y, Tanaka H, Tsuruta F, Dolmetsch R, Yamada M, Takahashi H, Kato T, Mori O, Eishi Y, Mizusawa H, Ishikawa K.

PLoS ONE 8:e50121 (2013)

< - 2012>

A novel NEDD8-binding protein modulates NF-kB signaling pathway.

Takashima O, Tsuruta F, Ebina M, Kigoshi Y, Nakamura S, Chiba T.

Arthritis Res Ther. 14(Suppl 1)(2012)

The ubiquitin E3 ligase activity of Cul3-KLHL7 is attenuated by an autosomal dominant Retinitis Pigmentosa causative mutation.

Kigoshi Y, Tsuruta F, Chiba T.

J.Biol.Chem. 286:33613-33621(2011)

The carboxy-terminal fragment of alpha(1A) calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells.

Ishiguro T, Ishikawa K, Takahashi M, Obayashi M, Amino T, Sato N, Sakamoto M, Fujigasaki H, Tsuruta F, Dolmetsch R, Arai T,

Sasaki H, Nagashima K, Kato T, Yamada M, Takahashi H,　Hashizume Y, Mizusawa H.

Acta Neuropathol. 119:447-464 (2010)

PIKfyve regulates CaV1.2 degradation and prevents excitotoxic cell death.

Tsuruta F, Green EM, Rousset M and Dolmetsch RE.

J.Cell.Biol. 187:279-294 (2009)

Highlighted in In This Issue by editorial

The C terminus of the L-type voltage-gated calcium channel CaV1.2 encodes a transcription factor.

Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L and Dolmetsch RE.

Cell 127:591-606 (2006)

JNK antagonizes Akt-mediated survival signals by phosphorylating 14-3-3.

Sunayama J, Tsuruta F, Masuyama N, and Gotoh Y.

J.Cell.Biol. 170:295-304 (2005)

細胞生存シグナルと死シグナルのバランスによる生死決定機構

砂山潤、鶴田文憲、後藤由季子　

実験医学 23: 2006-2011 (2005)

JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3proteins.

Tsuruta F, Sunayama S, Mori Y, Hattori S, Shimizu S, Tsujimoto Y, Yoshioka K, Masuyama N, and Gotoh Y.

EMBO J. 23:1889-99 (2004)

The phoshoatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria.

Tsuruta F, Masuyama N, and Gotoh Y.

J.Biol.Chem. 277:14040-7 (2002)

生存シグナルとアポトーシスシグナルのクロストーク

鶴田文憲、増山典久、後藤由季子

実験医学 18:1384-1390 (2000)

＜特許＞

三浦謙治、鶴田文憲
特願2019-142038
名称：細胞死抑制剤及び細胞死抑制方法
令和1年8月1日特許出願